On the reappraisal and redefinition of the scale of treatment of cardiovascular diseases (CVD) (hidrog) with Ayurvedic medicine techniques. (Revision of Ayurvedic Cardiology)

Recent studies in Ayurveda have given new hope for cardiovascular diseases, both therapeutic and prophylactic. With the advent of an increasing number of heart problems from a young age, it is time to explore the various options available in alternative areas of medicine. Herbs and nutritional supplements can play an important and even major role in preventive cardiology, according to published studies. This article explores the work of medicinal plants useful in cardiology that are described with special emphasis on RACONA, GOKSHURA, ARJUNA, AMALAKI, GUGGULU, ASHVAGANDHU, SARPAGANDHU, NIM. This work emphasizes the scope and scope of this practice in order to popularize the treatment and prevention options available in Ayurvedic literature.

INTRODUCTION: In the current scenario, cardiovascular disease (CVD) (hridrog) is considered one of the main causes of morbidity and mortality. Global burden of disease estimated at about 272 deaths per 100 thousand people. (even in India, the mortality rate increased by 59%). Current CVD management methods have their own limitations and the available allopathic chemicals have significant side effects with continuous / long-term use. Therefore, the need for the present time is to search for and use safe as well as effective treatment of cardiovascular diseases. And here, alternative therapies, such as Ayurvedic medicine techniques, can play a major role. A detailed description of the hridrog with its etiopathogenesis, as well as with treatment and drugs (chikitsa and ausadhi) is available in the language and in Ayurveda style. However, it includes not only Hriday or heart disease, but also some other associative conditions that affect heart function. Hydrogens due to krimi (bacteria, germs, parasites) have been described, even long before streptococcus affecting the heart valves were invented. Along with etiological factors, the lack of exercise, as well as psychological factors, are associated with chrydrogs.

Hriday sharara (anatomy / top. Anatomy of the heart), hriday sharakriya (physiology of the heart):

Hriday (heart) is one of the vital organs (target organs) or maha-marma, as explained in the ayur. Anatomy, which is responsible for providing and maintaining life. This is a unique location of Sadhak Pitta, Avalambaka Kapha and Vyan Vata, which together control not only the functions of the heart and circulatory system, but also the emotional aspect. It is also explained as a place for manas (reason). Hridaya is a pulsating organ placed in the chest cavity, in the mediastinum which is provided by the marmas of Hridaya, Mula Stan, Rohita Mill, Apasthamba and Anahata Chakra Pakrito. To the left of it are the pleecha (spleen), and to the left and right of the fusfus (lung) and to the right of it are yakrita (liver) and kloma (here the gall bladder). From the point of view of Ayurvedic embryology, it is generated from the maternal beginning, and Rakta and Kappa are the main participants in its initial formation. Symptoms of cardiovascular disease are also observed in disorders of other systems, such as digestive, respiratory, etc., and in many cases are an area of ​​enormous differential diagnosis. Ayurveda explains various as well as new views on etiopathogenesis and manifestations of CVD, as well as views on their management. A condition such as angina pectoris, characterized by angina pain and shortness of breath, resulting from obstruction of vata dosha by a distorted race of dhatu (race avrutta vata), Sushruta calls as hridshula (heart pain / angina pain / angina and unstable and stress). And the recommended management techniques for both hridshula and any hridrog in Ayurvedic sources are similar and settle on preventive measures with the importance of using different rasayanas. They are also aimed at the prevention of possible relapses in coronary heart disease (CHD).

Etiological factors of hidrog (hetu / nidan of cardiovascular disease):

 Ayurveda emphasizes many causative factors for the occurrence of chydrogs, such as excessive stress, excessive physical exertion, as well as excessive prescription (application) of treatment methods for shodhana (panchakarma-vaman, virechana, basti, nasya), etc. etc. Certain psychological factors under the Ayurvedic name of Sosh, causing common diseases, such as excessive anxiety, fear, stress, mental trauma, physical trauma, directly affect the heart, and all this can lead to a hidrog. Similarly, suppression of natural urges / urges (adharanya vegadharana), such as thirst, hunger, tears, shortness of breath, flatulence / air lowering, coughing, also contributes to CVD. The suppression of natural impulses causes the distorted functioning of Vata (avarana vata vikara), which can ultimately and insidiously lead to a hridrog. Ayurveda explains the metabolic syndrome in the context of shtul and prpmeha, which currently contributes to the problems of hridaya. In a detailed study into the rays of modern physiology, these factors indicate the fact of several other clinical conditions, leading ultimately to a hidrog. Researchers have identified several causes of the impact of psychological factors on the heart and its functions. Stress changes functions, for example, increases adrenaline rush, increases  blood pressure (BP) and heart rate (heart rate). These altered functions can damage the intima of the arteries, myocardial endothelium or increase the oxygen demand of the myocardium, which can cause angina pectoris in patients with coronary artery disease or chronic heart failure (CHF). 

Pathogenesis / pathophysiology (samprapti):

 Basically, two types of pathogenesis mechanism are explained for the onset of hidrog. The first of these is a “functional disorder” due to abnormal nidan sevan and abnormal agni. The status of Agni is very important, as this leads to the production of vishuddha rasa dhatu or rasa dhatu itself. Due to the malfunctioning of agni (digestive fire), ama (toxins) is formed in the form of different doshas (vata, pitta and kapha), ama is combined with rasa dhatu and samarasa dhatu is formed. This is dhatu dushti (spoiling of dhatu) which further leads to the duration of dushti (spoiling of channels or systems) and as a result, sorotrodha occurs in the rasabaha mouth (an obstruction or block in the circulatory system, in particular in the coronary arteries), damaged samarasa. Because of srotorodha, samarasa dhatu avrutta vata avarana appears (the distorted functioning of Vata samarasa dhatu); blood flow and hidrog are limited (IHD, angina pectoris). In case of short duration, dushi will be formed as well as sanga / rasa-meda vruddhi (atherosclerosis) leading to different angina pectoris and gulma (thrombosis) leading to acute myocardial infarction (AMI). Depending on the combination of doshas (ama) and dhatu, the manifestation and symptoms vary from ischemia to chest pain. When prana vayu (prana vata) is mixed in Samaras, this combination leads to acute pain in the pericardial region (angina pectoris) and shortness of breath of an acute nature. The second type describes any “organic change” in the structure of the heart with a change in structure. Conditions such as pericarditis, cardiomyopathy, mediastinal edema, etc., are serious conditions. Similar to the second type is the case of hidrog crime (in Ayurveda as CVD caused by microbes, bacteria, parasites or viruses – for example, infective endocarditis in allopathic medicine), as explained in the classic. Even hridaya is explained both as a place for vidradha (edema or abscess), as well as for gulma (education or thrombosis) when they manifest in subjects. Here, management depends mainly on the root cause. 

Hydrogens management principles: 

Ayurvedic medicine system is promising, and also gives hope for the management / treatment and prevention of developing heart diseases. Ayurveda, as always, places a special emphasis on both the preventive and therapeutic aspects, as always in all conditions, including in hridrogs. Here, in Ayurvedic cardiology, in the treatment of cardiovascular diseases, factors such as ama, agni, the state of the rasavach of time, ojas and even the psychological status of a person are considered. The anuloman of vata is very important, since vata is the dominant dosha in manifestation. Shodhana, if possible, after considering the ball (strength) is the best available option, followed by rasayana. Conditional shaman therapy is recommended for those who are not suitable for shodhana. Ayurvedic drugs acting on Hri are divided into Dipan, Pachan, Vatanuloman, Hrid, Bal and Rasayana. Management of psychological aspects is very important in parallel with other treatment methods.

Prevention of heart disease–Ayurvedic wisdom:

 Eating healthy is responsible for the prevention and, on the contrary, junk food is responsible for the manifestation of various pathological conditions. It is necessary to observe a daily diet according to the rules of eating according to ahaar vidhi (the rules of nutrition), mentioned in the classics, which is a cardinal aspect of preventive medicine. A preventive approach to cardiology can be divided into categories – Population Strategy (demographic strategy), Initial, primary and secondary prevention. 

Population Strategy (Demographic Strategy): 

The preventive approach is aimed at the whole population, and not just at individuals. The principles of Ayurvedic medicine, such as daily activities, which include regular yoga exercises (pranyama, asana), proper control of sarira (body), as well as manas (mind), vegas (natural urges or urges), sadvritta (following rules of behavior) and ahara bidhi (rules of nutrition) can be spread in society through various programs for public awareness at all levels of society.

Initial prevention:

prevention begins with the correction of the main lifestyle. Ayurveda has a rich collection of options to restore the true rhythm of nature, ensuring harmony with nature. Observance of the correct dinachary (daily routine), which includes the necessary individual yoga exercises (collecting asanas, pranayamas and meditation processes) regular physical. exercises (vyama), bath, prayer, meditation, proper ahara (proper diet) and ritucharya (seasonality mode), i.e. seasonal cleansing, as well as following sadvritta (behavioral rules) and passing the necessary achara rasayana (behavioral therapy) which includes Personal development and mental health care together help achieve this initial prevention that prevents potential risk factors.

Primary prevention: the

inclusion of a diet regimen, such as reducing the intake of salt, increasing the consumption of vegetables, fruits, legumes and cereals and lifestyle modifications (such as daily exercise, stress control, avoiding alcohol and smoking, etc.) are the task at the level of primary prevention to delay or prevent the onset of the disease. This is very important for those with families burdened with CVD stories.

Secondary Prevention: 

the purpose of secondary prevention is to prevent relapse and disease progression. To this end, Ayurveda offers various herbal remedies that help the best functioning of hriday at an optimal level, as well as offers ahara (diet), biharu (walking / traveling), psychological factors such as control of thinking (vicar) and the constant use of appropriate medicines. In the classical texts, several ganas, such as Hrdya Dashemaani Charaka, Parushakadi Ghana, Sushrut and Vidaryadi Ghana Wagbhata, are aimed at better control of the conditions of hrdaya. These three prophylaxis also with medicines (ausadhi) and panchakaoma (Ayurvedic detox-abhyanga, basti, nasya, etc.) provide svastha (health). So it is written in the swasthavritta section (ruled by health).

Medicinal plants and their role
(aridad hridrog- herbal cardio preparations:

 Ayurveda offers a variety of herbal medicines that can play a role in the management and prevention of many aspects of CVD.

Table No. 1: Cardioprotective drugs in

agnidipan and vataanuloman	lehanya	hridayaya Ayurveda	other useful drugs
Ajamoda, Hingu , Pippali, Sunthi, etc.	Vacha, Haridra, Guggulu, Darukharidra, etc.	Amra, Amrataka, Kakuwa Lakucha, Matulung Karamardak, Arjun, etc.	Gokshur, Pushkaramoola, Arjuna, Silajatu, Punarnava, Braham, Brahma , anapalandu

Table № 2: Examples of compounds with the action on Hrdaya

ghrutam	Quat	Gutikov	kumam	Rasayana	aristham
Pippilyadi GHM, Sunthi GHM, Ardzhunaghm	Pathyadi q, Dashamula q, Rasonadi Ap Vidaryadi q Hridayyarnava…….	Shilidzhitadi vati, Chandraprabha Vathi Prabhakar Vatirace	Arjuna tvak churna, Pippalyadi churna, haritakadi churna, Hinguvachai churna, Dviruttara churna	Amalakirasayana Agastharasayana, Bhallataka rsn. Pippalirasayana	Parthadyarishtam  Arjuna rist.

RESULTS OF PUBLISHED
RESEARCH WORKS:

The effect of some individual medicinal plants on hidrog (CVD) is described below based on the reported studies:

* RACONA (Allium sativum):
The effectiveness of racion (garlic) in CVD was more encouraging in experimental studies, as well as in several clinical trials. Allicin, the main biologically active compound of garlic, is the key to a beneficial effect on the cardiovascular system. It includes in its functions the reduction of atherosclerosis (sanga / rasa-meda vriddhi) (even prevents the need for stenting / CABG or provides prophylaxis after them), lipid-lowering effect (like statins and fibrates), inhibition of platelet aggregation (like antiplatelet agents – aspirin, clopidogrel), hypotensive effect (as ACE inhibitors, sartans, BMCC), even according to some reports, and antiarrhythmic effect (as β-blockers, amiodarone, propafenone). It also prevents oxidative stress and the associated ultrastructural changes caused by ischemic myocardial reperfusion. The study was conducted to evaluate the effect of 7.2 g of aged garlic extract compared to placebo in men with moderate hypercholesterolemia. This study reported a decrease in total serum cholesterol levels of 6.1% and 4.6% in LDL cholesterol with garlic compared to placebo. To this, according to numerous other data, the indicated effects were proved and verified, as well as compared with allopathic representatives. There was a conclusion: garlic showed these effects like these drugs, in many cases decently better and in all cases, compared with them, with significantly less or no side effects. The studies were carried out as expected with the parallel use of actual yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

GOKSHURA (Tribulus terrestris):
The biological properties of the tribulus include a diuretic effect (it is a good herbal diuretic like Punarnava but stronger). Kapkhagna is a preparation (reduces kapha) and consists of chemical compounds such as flabonoids, flavonol glycosides, steroid saponins, alkaloids, etc. Thanks to flabonoids, flabnol, saponins, alkaloids, it intensely releases nitric oxide (NO) from endothelium and nerve endings; relaxes smooth muscles and increases the inhibition of angiotensin converting enzyme (ACE) and therefore reduces blood pressure (hypotensive effect). Saponin having in it dilates the coronary vessels and improves circulation (vasodilating effect). In addition, due to glycosides and flabonoids, it is effective in supraventricular extrasystoles, atrial fibrillation (as an antiarimic drug), as well as in all classes of chr. heart failure (CHF – from 1 to IV F.K. according to NYHA). Experimental studies and scientific tests have very well proven these indicated properties, the effects are no worse in effect than allopathic diuretics (thiazide hydrochlorothiazide, loop-furasemide or trosemide), ACE inhibitors (lisinopril, perindopril), or glycosides (digoxin – already in rarely used by the world), however, a gokshura has significantly fewer or no side effects. With a prolonged use of courses with arjuna, the following has been checked and proved: the risk of myocardial infarction (MI) and its recurrence is significantly reduced. The studies were conducted as expected with the parallel use of the actual exercises of yoga, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

 ARJUNA (Terminalia arjuna):
Arjuna is introduced in Ayurveda as Hrida or Hrida Ausadhi according to Wagwat and its chemical composition is enriched with Arjunetin and Tannin. Its race (taste) is astringent and bitter, the guna (quality) is rough, vipak (effect after digestion) is sharp and virya (energy) is cooling. It is mainly a reducer of kapha and pitta (kapha-pittaghna) but at a certain dosage it also reduces vata (tridoshahara – reduces all 3 doshas). It lowers cholesterol, triglycerides, has antiaggregant properties and thus has a chance of developing thrombosis and, as a result, has an antisclerotic effect (anticholesterol, antiplatelet agent) (wrudha and gulma race / honey). And all this is due to the kapghagna of quality and the availability of arjunin and tannin. The facts are proven by clinical trials. Experimental scientific studies show, harden and prove a series of phenomena such as: Normal hypotensive effect (reduces blood pressure), reduces episodes of unstable angina and improves the functional class of stable angina, reduces the risk of myocardial infarction and stroke. Used as a diuretic. It perfectly reduces myocardial oxygen demand and that it better reduces episodes of anginal pain no worse than nitroglycerin / nitrates (without a headache). Reduces (inhibits) necrosis and apoptosis. It has positive inotropic dromotropic effects, a negative chronotropic effect, reducing heart rate (pulse) and a positive lusitropic effect (these effects increase with ashwagandha) and the main thing is that these effects are not worse and even better in case of prolonged use than b-blockers, BMCC, dopamine, cardiac glycosides and the more completely without side effects. Arjuna improves cardiac muscle function and subsequently improves pumping activity of the heart (especially in the form of syrup or decoction and with ashwagandha) (ECHO-KG often showed an improvement in the ejection fraction (FB) and often positive modulations of the areas of dyskipokinesia after a heart attack). In a hypertensive crisis, a decoction of bark powder turned out to be (with sarpagandha) more effective than treating it with chronic heart failure. Studies have proved the advantages of terminal arjuna in treating coronary artery disease / coronary artery disease, heart failure and hypercholesterolemia as well as cardioprotective activity due to its cleansing activity free radicals and the same presence of arjunetin.

The study proved that arjuna has an excellent cardioprotective effect (cardioprotector) from the damage caused by the introduction of caffeine.

With Akik Pisti, Ashwaganha, Brahmi, Dadima, Kutka, him, Gokshura, Guggul, very good results were recorded by doctors in India in the USA in the following pathological cases:

Coronary heart disease (CHD): angina pectoris (Angina Pectori) voltage of any functional class, unstable angina pectoris; arrhythmia (pitta disorder) (fibrillation, extrasystole, sinus and supraventricular tachycardia), disorders of the conduction system (AB blockade, CVD), essential and secondary arterial hypertension (raccapcha – vrudha), postinfarction period, aortic and mitral insufficiency , cardiomyopathies (hypertrophic, dilitational, restrictive), chronic heart failure (all NYHA classes), conditions after stenting and shunting (CABG) (it was even possible in many cases to cancel stenting and shunting of education).

It was observed and noted that the comparative effectiveness of arjuna (with mono-intake or with other herbal preparations) with antiplatelet agents, Ing.-ACE, BMKK, statins, nitrates, b-blockers, amiodarone, sartans is not worse and even better especially with long courses of administration and without comparatively side effects. The studies were conducted as expected with the parallel use of the actual exercises of yoga, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

AMALAKI / AMLA (Embilica officinalis):
In Ayurvedic medicine, amalaki is one of all available effective rasayan, which, according to the Dravagun (Ayurvedic pharmacology), is effective in the treatment and prevention / rehabilitation of respiratory, cardiovascular, rheumatic and rheumatological diseases, as well as with diabetes. Various experimental studies have shown and proved its good antioxidant and lipid-lowering effects. Clinical trials have proven that amalaki produce significant lipid-lowering effect along with a decrease in blood pressure (BP). It also provides significant protection against atherosclerosis and coronary heart disease (CHD). The preparation contains a large amount of vitamin C in its natural form, as well as cytokine-like substances (identified as zeatin), Z-riboside, Z-nucleotide, flavonoids, pectin and 30% tannin. Studies have proven that flavanoid and pectin lower cholesterol in human serum and fight against atherosclerosis. According to other sources, due to the presence of vit. C, nucleotide, riboside, flabonoids improves local LV contractility (with dyskinesia, akinesia after AMI), as well as the functions of the heart valves working together with arjuna, ashwagandha and akik write. The studies were conducted as expected with the parallel use of actual yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

GUGGUL / GUGGUL (Commiphora mukul):
The chemical composition of Commiphora mukul is guggulsterone E and Z1, guggulipid, oleresin. Its race (taste) is bitter and sharp, guna (quality) is light and thin, vipak (effect after digestion) is sharp and virya (energy) is warming. It suppresses (soothes) kapha and vatu (kapha-vataghna), increases pitta, and can reduce pitta (tridoshahara – reducer of all three doshas). Due to the thin (sukshma) guna and due to guggulsterone E, oleresin, it easily penetrates the cellular level by itself and together with other herbs (trifala, kanchanar, punarnava) and provides detoxification and rejuvenation – an ideal cleansing and anti-aging agent. It has a diuretic effect. Natural antioxidant, blood disinfectant (Rakshoghna). Thanks to oleresin, guggul has a high anti-inflammatory effect.

Controls agni (agni sthana) – improves appetite (dipan) gives strength (bala). Due to kapghagna pravaba, guggulsterone E and Z1, acute race and vipak, it perfectly helps to reduce weight (medohara effect) and due to guggulsterone E and Z1, guggulipid, acute race and vipak, warming virya and tar in it, it regulates the lipid spectrum (good reduces LDL, VLDL, triglycerides, increases HDL), reduces atherosclerosis (sanga / race – vruddha honey). It also has an antiplatelet property and reduces the risk of thrombosis (gulma). Strictly by scientific tests, these facts are proved, stated and reasoned. Various Ayurvedic experimental studies in India, Europe, USA

indicated the following: shudha guggulu and other Ayurvedic compounds, such as navaka guggulu, pushkara guggulu, trikat gave a very good lipid-lowering effect in blood serum. In the lipid profile, there is a good decrease in LDL, VLDL, triglycerides and an increase in HDL. Good fight against hypercholesterolemia (rasa-meda vriddhi) of all gr. (according to Fredrison) were seen, especially against the particular risk of 2b gr. With long courses, statins and fibrates could also be canceled (from these two together the deterioration of liver enzymes, ravdomyolysis, cholelithiasis). The same Ayurvedic options were no worse and completely without side effects. An experiment that was done on albino rats reported that shuddha guggulu has cardioprotective activity (as a cardioprotector like arjuna), as it increases HDL levels and lowers triglycerides well. Researchers reported that with nim and arjuna, guggulu fights well against atherosclerosis (sanga / rasa-meda vriddha) of the coronary vessels and reduces stenosis of these arteries to the desired level that can be canceled stenting and shunting (CABG) (in India, many cases have been recorded); It is also good for prevention after these manipulations / operations.

In addition to lowering serum lipids, Pushkara Guggulu well reduced anginal pain and shortness of breath, and when he saw it together with arjun, shuddha guggul, akik pishti, neem, ashwagandha and it was possible to cancel nitrates (many side and headaches) and ranolazine with long courses and virtually no chemical effects compared to nitrates and ranolazine.

Guggulu horses along with vrikshamla, haritaki, medohar, suddha showed amazing results with weight loss in the treatment of overweight and obesity of any degree (BMI according to WHO). And with short-term or long-term doses, the results were without side effects and it was possible to cancel such as orlistat, sibutramine with many side effects, or get around without them. It was also confirmed that the guggul (especially shuddha) in conjunction with the gokshura / punarnava and arjuna is great in the treatment of all classes of the Chr. heart failure (CHF-1 to IV F.K. NYHA), reducing shortness of breath, swelling. The studies were conducted as expected with the parallel use of relevant yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

ASHVAGANDA (Withania somnifera):
According to dravyagun, its chemical composition contains vuitaferin A, vuitasomniferin, its race is astringent and bitter, light guna, sweet vipak, warming virya. Due to this and the fact that it is a reducer of vata and kapha (vata-kapghagna), it lowers blood pressure (hypotensive effect) (neurogenic origin) (vuitaferin and vuitasomniferin), has a negative inotropic effect and a negative chronotropic effect, reducing heart rate (pulse) and positive the lusitropic effect (with arjuna) (due to vuitasomniferia), together with arjuna, has an antiatherosclerotic effect in the arteries of the heart and brain, and the combined action regenerates cardiomyocytes well after and nfarkta. These facts and effects have been proven by various scientific studies. Wedge. tests also confirm that it is no worse with hypertension and a hypertensive crisis (neurovegetative option) together with Sarpagandha than b-blockers, BMKK, ing.-apf, moxinidine, sartans, with arrhythmia (atrial fibrillation (tachysystolic form), sinus and supra-ventricular tachycardia) than propafenone, amiodarone, b-blockers, with prolonged use and without side effects, it can also replace chemo options. There are also facts about an excellent improvement in the state of the post-infarction period, as well as by ECHO-KG, a significant improvement in the areas of myocardial hypo-dyskinesia and the condition of the valves when combined with arjuna, neem, akik pishti, brahmi was confirmed. The studies were conducted as expected with the parallel use of relevant yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

BAT / BAT (Azadirachta indica):
Because of the bitter and astringent race, the light and rough guna, the acute vipaka and the cooling virya, is kapha-pitagna (kapha and pitta reducing). Due to the nimbin and tannin in it and its ability to produce dhatu rakt, he is considered in Ayurveda as a very good antiaggregant (disaggregant) (gulmaghna – reduces gulma) i.e. inhibits platelet aggregation well. To the same nimbus also gives a slightly hypolipidemic (against raru-honey vruddhi) effect.

Clinical trials have proven its antiplatelet effect is not worse than aspirin and clopidogrel with prolonged use, the same chance of internal bleeding, exacerbation of gastritis and ulcers (especially in the age group over 65) is excluded.

Scientific studies have confirmed the facts that, together with shuddha guggul (or guggul), it gives a good anti-atherosclerotic effect and it is possible to replace them with antiplatelet agents and statins in case of contraindications in a long course. These facts were proved in various coronary heart disease, after a heart attack, with thrombophlebitis, etc. Its antibacterial effect is also welcomed in various CVDs (hridrog) (for example, inf. Endocarditis, valvular pathologies) in Ayurvedic cardiology. The studies were conducted as expected with the parallel use of relevant yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

SARPAGANDHA (Rauwolfia serpentina):
Rauwolfia serpentina consists of reserpine, serpentine, ajmaline.

Its race is bitter, guna rough, vipak sharp and virya warming and, as a result of these qualities, it Suppresses (soothes) kapha and vata (kapha-vatghna). It well reduces blood pressure and its hypotensive effect due to the presence of reserpine, serpentine and ajmaline.

It has negative inotropic and chronotropic effects, it reduces the heartbeat (heart rate) due to reserpine, serpentine and watatah effect. Experimental studies have ascertained the substance of these facts, as well as proved the following (by doctors and scientists in India, the USA, Europe):

Essential (primary) and secondary arterial hypertension decently went to treatment with sarpagadha and panchakarma and no worse with ingb-ACE, BMCC, sartans, a-blockers, moxinidine, b blockers. Control of a hypertensive crisis (neuro-vegetative option) with the help of sarpagandha, arjuna, ashwagandha gave good positive results (especially when taking their decoction) and no worse than captopril and other ingb. – ACE, BMCC (dihydopyridine-nephi amlodipine), furasemide, a / b-blockers, b-block, a-block, clonodine or perf.vasodilators) only not in urgent conditions requiring emergency care. In the treatment of various types of arrhythmias (fibrillation, extracystolia, sinus and supraventricular tachycardia), it with brahmi, ashwagandha, shankkhapushpi were not even good and relatively good and not worse than on the level of b-blockers, amiodarone, propafenone with long-term use. In comparison with chemical analogues, they have no side effects or they are minimal. The studies were conducted as expected with the parallel use of relevant yoga exercises, the necessary procedures of panchakarma, ahara vidhi, sadvrutta, svasthavrutta, meditation.

Areas for future research:

There is a huge need for a broad study to find out the actual connection between chrydrogs and modern cardiac pathologies, to prove the effectiveness of many herbs and formulations described in the classics in the chondrog section, to find the components responsible for specific actions, and to understand the doses, potential risks and benefits with their possible toxicological studies for various heart problems. A detailed study of plants and their components will lead to the development of new compositions for the treatment of heart disease much faster and more successfully, as well as with significantly minimal side effects or without them.

CONCLUSION:

Discussions and decisions about cardiovascular diseases are recorded in the context of hidrog in Ayurveda. A series of Ayurvedic herbs and supplements act as a complement to the prevention and treatment of cardiovascular disease. Herbs such as RACONA, GOKSHURA, ARJUNA, AMALAKI, GUGGULU, ASHVAGANDHAH, SARPAGANDHAH, BAT and their compositions are safe (without side effects) and highly effective in the treatment of CVD (hidrog). Such drugs have a lipid-lowering property, hypotensive effect, antiatherosclerotic effect, are cardioprotectors, antiaggregants, and. However, you should follow a balanced diet, exercise and avoid bad habits such as smoking, drinking alcohol, coping with stress, and doing yoga and brushing yourself, treating yourself with panchakarma so that we can prevent hidrogs. The eternity of Ayurveda lies in the sense of its great attachment which is embedded in its (Ayurveda) approaches to diseases, people and life in general. The scientific Ayurvedic understanding of various clinical aspects, if applied, in solving problems of cardiovascular diseases, can work wonders in cardiology issues both at the medical and preventive levels. We should seriously focus on possible studies and their results for further conclusions, and thus we will reconsider the field of Ayurvedic cardiology in order to overestimate / redefine the scope of treatment for CVD, i.e., hidrogs using Ayurvedic medicine methods are much more successful, promising and without side effects. It remains for modern allopathic medicine to only be friends with Ayurvedic medicine, and not to resist it and have an integrative approach to diseases, patients and, in general, medicine in order to improve the health of the world’s population.

Bibliography:

Main sources:

1. Jithesh Madhavan, Assistant Professor and Head of the Department of Research at Kajajictitsa and Graduate School at Manovijnan, VPSV, Ayurveda Institute of Medicine, Kottakkal, Kerala, India.
2. Fasnath Arabi, graduate student, Department of Manovijnan, VPSV Institute of Ayur.medicine, Kottakkal, Kerala, India. Kerala, India.
3. Jitesh et al. Asian Journal of Pharmaceutical Research and Development.
4. ISSN: 2320-4850 CODEN (USA): AJPRHS.

Допольнительные источники:

1. Prabhakaran D, Jemon R, Roy; Cardiovascular diseases in India: current epidemiology and future directions. April 2016 nineteen; 133 (16): 1605-20.
2. Sharma P. Dalhan Commentary by Sushrut Samhita, Sarir Sthan, chapter 4, verse No. 30 Varanasi: Chauhambha Visvabharti Publications; 2005.
3. Yadavji Tricamji Acharya, Agnishakrita Charaka Samhita, Chakrapani, Chikitsasthan26 / 77, Varanasi, Chauhambha Sanskrita Sansthan, 2009.
4. Hemadri; Sarvanga Sundhara Arunadatta Commentary on Ashtang Hridaya; respectively sthana, chapter 4, verse No. 3-20; Reprint of Varanasi (India): Chaukambha Orientalia: 2005.
5. Pratibha Mamgain and RH Singh; a critical study of the concept of coronary heart disease in Ayurveda; The Ancient Life Science, Volume XIII, Nos. 1 and 2, July-October 1993
6. Dr. P. Sudhakar Reddy, MD Bina; Cardiovascular Disease Prevention Overview at Ayurveda wsr in Hrid; International Journal of Ayurveda and Herbal Medicine 7 (1) January-February 2017 (2429-2435).
7. Dr. Subrat Bhutia; the role of certain medicinal plants in cardiovascular diseases; Indian Journal of Medical Research and Pharmaceutical Sciences.
8. Biswas Gop; Comparative clinical study of the hypolipidemic efficacy of Amla with a 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin; Indian J Pharmacol. 2012 March-April; 44 (2): 238-242.
9. Sapra Umesh Kumar; The antihyperlipidemic effect of Panchatikta ghana and Suddha guggulu – an experimental study, the journal of Ayurveda and Holistic medicine, April 2013
10. Internal diseases, cardiovascular system, G. Roitenberg and A. V. Strutinsky
11. Cardiology, diagnostic criteria, and current time treatments, Michael H. Crawford.
12. Ayurveda for practitioners of modern medicine; Kumud S. Nagral.
13. Sharira Kriya Vignan; Chitta Ranjan Das. 1 and 2 parts.
14. Ayurvedic Panchakarma.
15. Ayurvedic Panchakarma Vignan; Shridhar Kasture.
16. Internal diseases; Moiseev V.S.
17. Endocrinology; Grandfathers, Melnichenko, Fadeev.